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伊布利特半富马酸盐,Ibutilide hemifumarate salt;≥98% (HPLC)

别名:富马酸伊布利特;(±)-N-4-4-(Ethylheptylamino)-1-hydroxybutylphenyl-methanesulfonamide hemifumarate salt, Corvert

Empirical Formula (Hill Notation): C20H36N2O3S · 0.5C4H4O4 CAS号: 122647-32-9 分子量: 442.61 MDL编号: MFCD01715410 PubChem化学物质编号: 329815470 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): I9910
CAS号: 122647-32-9
MDL号: MFCD01715410
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$287.09

说明

伊布利特半富马酸盐被认为是新一代“纯”III 类抗心律失常药。 伊布利特结合并改变 hERG 钾通道、延迟内向整流钾 (IKr) 通道和 L 型(二氢吡啶敏感)钙通道的活性。

包装

10, 50 mg in glass bottle
 

生化/生理作用

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.
 

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

属性

测定

≥98% (HPLC)

形式

solid

颜色

off-white to tan

溶解性

H2O: >20 mg/mL

创始人

Pfizer

储存温度

room temp

SMILES string

OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c2ccc(NS(C)(=O)=O)cc2

InChI

1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key

PCIOHQNIRPWFMV-WXXKFALUSA-N

Gene Information

human ... KCNH2(3757)

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

危害代码

Xn

风险声明

22

RIDADR

NONH for all modes of transport

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16