人IgG,IgG from human serum;reagent grade, ≥95% (HPLC), buffered aqueous solution

Human IgG;IgG来源于人类血清;MDL number MFCD00163923 NACRES NA.46
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): I2511
MDL号: MFCD00163923
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IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。 它由B细胞分泌,存在于血液和细胞外液中,可防止细菌,真菌和病毒引起的感染。 母体IgG通过胎盘转移到胎儿,这对新生儿免疫防御感染至关重要,胎盘通过沉淀和凝胶过滤技术从正常人血清中纯化而来。


免疫球蛋白G(IgG)调节免疫反应,例如吞噬作用,并且还参与自身免疫性疾病的发展。 IgG1调节小鼠中的补体固定。

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections[6]
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.


Purified human IgG has been used :-
• as blocking antibody for flow cytometry[3]
• as negative control in chromatin immunoprecipitation assays[4]
• to precipitate IgG in human larynx epidermoid carcinoma cells by immunoprecipitation[2]
• as a standard in enzyme-linked immunosorbent assay[5]

Biochem/physiol Actions

Immunoglobulin G (IgG) regulates the immune responses such as phagocytosis and is also involved in the development of autoimmune diseases.[1] IgG1 regulates complement fixation in mice.[5]

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Quality Level200
gradereagent grade
assay≥95% (HPLC)
formbuffered aqueous solution
shipped indry ice
storage temp.−20°C


RIDADR NONH for all modes of transport
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32