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人血清白蛋白 [人白蛋白],Albumin human [rHSA];lyophilized powder, essentially protease free, ≥96% (agarose gel electrophoresis)

别名:人血清蛋白;人白蛋白;白蛋白来源于人;Albagen™;rHSA;Human serum albumin;Human albumin

CAS号 70024-90-7 EINECS 编号 274-272-6 MDL number MFCD00081418 NACRES NA.25
货号(SKU): A4327
CAS号: 70024-90-7
MDL号: MFCD00081418
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$215.42

产品描述

General description

Albumin is the most copious protein in blood plasma. Produced in the liver,[4] serum albumin serves as a carrier protein for biomolecules like as fatty acids, amino acids, and steroids.

This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:
• Essentially protease-free / low protease content
• Low alkaline phosphatase content
• Low peroxidase content

Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.

Protease-free HSA is especially useful for applications like:
• Enzyme assays
• Protein-based assays
• Protease-sensitive techniques such as:
(a) Enzyme immunoassay (EIA)
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)

Application

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia.[3] It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.[4]
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin.[2] It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.[1]

包装

1 g in glass bottle

500 mg in glass bottle

Biochem/physiol Actions

血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。

Features and Benefits

• Low protease activity / essentially protease-free (≤ 0.0001 units/mg protein)
• Low alkaline phosphatase activity (≤ 0.001 units/mg protein)
• Low peroxidase activity (≤ 0.001 units/mg protein)

Preparation Note

Prepared from A1653

Other Notes

查看更多关于 人血清白蛋白的信息

性质

Quality Level200
biological sourcehuman
assay≥96% (agarose gel electrophoresis)
formlyophilized powder
mol wtmonomer calculated mol wt 66478 Da
application(s)tissue culture: suitable
impuritiesHIV I and HIVII, HCV and HBsAg, tested negative
solubilityH2O: soluble 50 mg/mL
foreign activityAlkaline phosphatase ≤0.001 units/mg protein
Peroxidase ≤0.001 units/mg protein
Protease ≤0.0001 units/mg protein
storage temp.2-8°C
Gene Informationhuman ... ALB(213)


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
闪点(华氏) Not applicable
闪点(摄氏) Not applicable
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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