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人类热休克蛋白60,Heat Shock Protein 60 human [HSP 60];recombinant, expressed in E. coli, buffered aqueous solution, ≥95% (SDS-GE)

基因HSP60(热激蛋白60)被定位到人类染色体2q33.1,它是线粒体蛋白。
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): H7158
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¥12,812.29

产品描述

General description

The gene HSP60 (heat shock protein 60) is mapped to human chromosome 2q33.1.[1] It is a mitochondrial protein. HSP60 is induced under various stress conditions, including DNA damage, oxidative stress and heat shock.[2] HSP60 is also referred to as HSPD1 (heat shock protein family D member 1).

Biochem/physiol Actions

HSP60 (heat shock protein) works together with the cochaperonin HSP10 to allow protein folding of mitochondrial-imported proteins. It is involved in brain myelination and pathogenesis of hypomyelinating neurodegenerative disease.[3] It also enhances proinflammatory response in cells, including macrophages, dendritic cells and endothelial cells.[4] Mutation in HSP60 is linked with hereditary spastic paraplegia (SPG13).[1]

Physical form

Solution in Dulbecco′s buffered saline

性质

biological source  human
recombinant  expressed in E. coli
assay  ≥95% (SDS-GE)
form  buffered aqueous solution
shipped in  dry ice
storage temp.  −70°C
Gene Information  human ... HSPD1(3329)


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-70°C超低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10