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人甲状腺球蛋白,Thyroglobulin human [hTg];≥95% (SDS-PAGE)

别名:human Thyroglobulin; CAS号: 9010-34-8 EC 号: 232-721-3 MDL编号: MFCD01324794 NACRES: NA.56
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): T6830
CAS号: 9010-34-8
MDL号: MFCD01324794
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€292.26

说明

人甲状腺球蛋白 (Tg) 是一种 660 kDa 的二聚体蛋白质,由甲状腺产生并完全在甲状腺内使用。人类甲状腺红蛋白被甲状腺用于产生甲状腺激素甲状腺素 (T4) 和三碘甲状腺原氨酸。患有桥本氏甲状腺炎或格雷夫氏病的患者经常会产生针对人类甲状腺球蛋白的抗体。
人甲状腺球蛋白 (Tg) 是一种 660 kDa 的二聚体蛋白质,由甲状腺产生并完全在甲状腺内使用。人类甲状腺红蛋白被甲状腺用于产生甲状腺激素甲状腺素 (T4) 和三碘甲状腺原氨酸。患有桥本氏甲状腺炎或格雷夫斯氏病的患者经常会产生针对人类甲状腺球蛋白的抗体。血液中的甲状腺球蛋白水平可用作某些甲状腺癌和 Graves 病的肿瘤标志物。

甲状腺球蛋白已被证明可诱导人外周血单核细胞中血小板激活因子的表达,在某些甲状腺疾病患者中发现该因子升高。

一般描述

Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Grave′s disease, frequently develop antibodies against human Thyroglobulin.
Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Graves′ disease, frequently develop antibodies against human Thyroglobulin. Thryoglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and in Graves′ disease.
 

包装

1, 5 mg in glass bottle
 

生化/生理作用

Thyroglobulin has been shown to induce expression of platelet activating factor in human peripheral blood mononuclear cells which is found elevated in some patients with thyroid disease.
 
 

属性

质量水平

200

生物来源

human

测定

≥95% (SDS-PAGE)

形式

lyophilized solid

应用

cell culture | mammalian: suitable

储存温度

2-8°C

Gene Information

human ... TG(7038)

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16