二(2-羟基阿托伐他汀-d5)钙盐，di(2-Hydroxy Atorvastatin-d5) Calcium Salt

图片 二(2-羟基阿托伐他汀-d5)钙盐，di(2-Hydroxy Atorvastatin-d5) Calcium Salt
CasNo：265989-47-7；分子式:C66H58D10CaF2N4O12；分子量:1197.42
制造商品牌: 加拿大TRC
货号（SKU）: H828932
CAS号: 265989-47-7
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Product Description

Catalogue NumberH828932
Chemical Namedi(2-Hydroxy Atorvastatin-d5) Calcium Salt
Synonyms(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-d5-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1)
CAS Number265989-47-7
Alternate CAS #265989-46-6 labeled free acid: 777841-55-1
Molecular FormulaC₆₆H₅₈D₁₀CaF₂N₄O₁₂
AppearanceOff-White to Pale Beige Solid
Melting Point>152°C (dec.)
Molecular Weight1197.42
Storage-20°C Freezer, Under inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
CategoryBuilding Blocks; Chiral Molecules; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Applicationsdi(2-Hydroxy Atorvastatin-d5) Calcium Salt is the labeled analogue of di(2-Hydroxy Atorvastatin) Calcium Salt (H828930), a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
ReferencesKearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
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储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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