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乙二胺四乙酸二钠盐 [EDTA二钠盐],EDTA-Na2;reagent grade, 98.5-101.5% (titration)

别名:乙二胺四乙酸二钠盐二水合物,EDTA Na2,乙二胺四乙酸二钠二水合物,依地酸,依地酸二钠,依地酸盐二钠盐二水合物,EDTA2钠盐,EDTA钠盐,Ethylenediaminetetraacetic acid disodium salt dihydrate;Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2

CAS号 6381-92-6 经验分子式(希尔表示法) C10H14N2Na2O8 · 2H2O 分子量 372.24 Beilstein/REAXYS Number 3900609 EINECS 编号 205-358-3 PubChem Substance ID 24894708 NACRES NA.77
货号(SKU): ED2SS
CAS号: 6381-92-6
MDL号: MFCD00150037
增值税发票 √ 免费货运 [顺丰 联邦] √
4 352,16 ₽

产品描述

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions to form an octahedral complex especially with cations.[1] Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.[5] It enhances the antibacterial activity of lysozyme.[2] EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.[3] EDTA chelation therapy protects from lipid peroxidation events in liver fibrosis.[4]

Application

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used as a component of the plasma membrane resuspension buffer,[6] inhibitor′s preservative solution (IS)[7] and luciferase activity assay mix.[8]

二价阳离子的螯合剂。抑制需要二价阳离子才能具有活性的酶,例如金属蛋白酶。

包装

1 kg in poly bottle

2.5, 5 kg in poly drum

50, 100, 250, 500 g in poly bottle

Biochem/physiol Actions

可通过二价金属离子与 EDTA 的螯合而有效抑制锌依赖性金属蛋白酶以及由钙稳定的其他蛋白酶。其他螯合剂(例如对钙特异性的 EGTA 以及对锌高度特异性的 1,10-菲罗啉)可用于靶向这两种不同类型的蛋白酶

性质

Quality Level200
biological sourcesynthetic (organic)
gradereagent grade
assay98.5-101.5% (titration)
formpowder
mp248 °C (dec.) (lit.)
solubilityH2O: soluble, clear, colorless
storage temp.room temp
SMILES stringO.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
InChI1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
InChI keyOVBJJZOQPCKUOR-UHFFFAOYSA-L


安全信息

符号
信号词
Warning
危害声明 H332 - H373 - H412
靶器官 Respiratory Tract
个人防护装备 EyeshieldsGlovestype N95 (US)
危害码 (欧洲) Xn
风险声明 (欧洲) 20-48/20
RIDADR NONH for all modes of transport
WGK德国 WGK 2
RTECS AH4410000
闪点(华氏) Not applicable
闪点(摄氏) Not applicable
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 300 | 欧洲Eur. ≥ 90 | 東京Tokyo ≥ 36 | 香港与北京 ≥ 99