三氟乙酸，Trifluoroacetic acid [TFA]；for synthesis, ≥99% (acidimetric)

Trifluoroacetic acid is widely used in organic synthesis as a solvent, catalyst and reagent. It is a strong acid and low boiling point reagent. It can be used as a catalyst for a variety of reactions such as rearrangements, functional group deprotections, oxidations, reductions, condensations, hydroarylations and trifluoromethylations.[1]

 

Trifluoroacetic acid can be used as a catalyst

• In the direct conversion of cyclohexanone to caprolactam using acetonitrile as the additive.
• In the synthesis of 1,2,4,5-tetrasubstituted imidazoles by four-component condensation of benzil, aldehydes, amines, and ammonium acetate.

Trifluoroacetic acid can also be used

• In the synthesis of d-α-Tterpineo from d-limonene by Markovnikov addition followed by hydrolysis.

Trifluoroacetic acid can be used as a catalyst due to its

• High acidity
• Easy elimination
• Good solubility in organic solvent and in water.

含量测定（酸量法）： ≥ 99.0 %
密度（d 20 °C/4 °C）：1.487 - 1.490
鉴别（IR）：符合检验