sevenspikes.themes.common.filters
sevenspikes.themes.common.closemenu

丁基-S琼脂糖凝胶6FF,Butyl-S Sepharose 6 Fast Flow

Butyl-S Sepharose 6 Fast Flow 是 Sepharose Fast Flow 疏水相互作用色谱 (HIC) 系列中疏水性最低的树脂,在纯化过程的初始阶段去除大量杂质特别有用。17097810;17097803;17097804;17097802
货号(SKU): 17097803
增值税发票 √ 免费送货 √ 订货电话:010-68689484
$1,836.24

Butyl-S Sepharose 6 Fast Flow is the least hydrophobic resin in the Sepharose Fast Flow hydrophobic interaction chromatography (HIC) range and is particularly useful during the initial stages of a purification process to remove the bulk of impurities

在相对较低的盐浓度下结合和洗脱相对较强的疏水性分子
久经考验的 Sepharose Fast Flow HIC 系列中疏水性最低的树脂
从 CHO 细胞中纯化重组乙型肝炎病毒表面抗原
与工艺规模的生物制药制造商合作开发和优化
基础基质的亲水性确保了低水平的非特异性结合。
Butyl-S Sepharose 6 Fast Flow 是 Sepharose Fast Flow HIC 平台的一部分,该平台在近几十年来一直是 HIC 色谱的工业标准。

Butyl-S Sepharose 6 Fast Flow 由通过硫醚键用丁基修饰的交联 6% 琼脂糖珠组成。与 Butyl Sepharose 4 Fast Flow 和其他 HIC Sepharose Fast Flow 产品相比,它将表现出不同的选择性。

这种树脂设计用于在相对较低的盐浓度下结合和洗脱相对较强的疏水性分子。 Butyl-S Sepharose 6 Fast Flow 在分离过程的初始阶段特别有用,可以去除大量杂质,而无需对样品进行严格的调节(例如调节 pH、盐浓度等)

Butyl-S Sepharose 6 Fast Flow 有多种不同的散装尺寸和方便的预包装形式,便于放大和工艺开发。作为 BioProcess 树脂系列的一员,Butyl-S Sepharose 6 Fast Flow 可通过供应安全性和全面的技术和法规支持满足工业需求

 

  • Binds and elutes relatively strong hydrophobic molecules at comparatively low salt concentrations
  • The least hydrophobic resin in the well proven Sepharose Fast Flow HIC range
  • Purifies recombinant Hepatitis B virus surface antigen from CHO cells
  • Developed and optimized in cooperation with a process-scale manufacturer of biopharmaceuticals
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding.

Butyl-S Sepharose 6 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades.

Butyl-S Sepharose 6 Fast Flow is composed of cross-linked 6% agarose beads modified with butyl groups via a thio-ether linkage. It will exhibit a different selectivity compared to Butyl Sepharose 4 Fast Flow and other HIC Sepharose Fast Flow products.

This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively low salt concentrations. Butyl-S Sepharose 6 Fast Flow is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g. adjustment of pH, salt concentration etc.)

Butyl-S Sepharose 6 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Butyl-S Sepharose 6 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support

 

ParameterButyl-S Sepharose 6 Fast Flow, 1 L
BioProcess resinYes 
LigandButyl-S 
Particle size, d50V1~90 µm 
Matrix6% cross-linked agarose 
Particle Size45 µm-165 µm 
Ligand densityApprox 10 µmol Butyl-S/ml medium 
pH stability, operational23–13 
pH stability, CIP32–14 
Pressure/Flow SpecificationBase matrix: 250-400 cm/h, 100 kPa, XK 50/60 column, bed height 25 cm 
Storage4 to 30°C, 20% Ethanol 
Chemical stabilityStable in commonly used aqueous buffers: 1 mM HCl, 1 M NaOH, 30% isopropanol, 50% ethylene glycol, 70% ethanol, 6 M guanidinehydrochloride, 8 M urea 
Certificate of AnalysisYes 
LicensingFor licensing information, see the Licensing Statements page in the About Us section. 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16