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丁卡因盐酸盐 [盐酸丁卡因]，Tetracaine hydrochloride；Pharmaceutical Secondary Standard; Certified Reference Material

别名：盐酸丁卡因标准品；4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯；盐酸氨甲卡因；4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride

Empirical Formula (Hill Notation): C15H24N2O2 · HCl CAS号: 136-47-0 分子量: 300.82 MDL编号: MFCD00038912 PubChem化学物质编号: 329823150 NACRES: NA.24

制造商品牌: 西格玛 Sigma-Aldrich , 默克色谱科 Supelco

货号（SKU）: PHR1129

CAS号: 136-47-0

MDL号: MFCD00038912

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目录价.SKU-Variant

¥768.77

数量:

说明

一般描述

Tetracaine hydrochloride is a local anesthetic drug and an ester derivative of p-amino benzoic acid.[1] It acts by interfering with the entry of sodium ions into nerve cells and is one of the commonly used topical anesthetics.[2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Tetracaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.[3][4][5][6]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

眼用局部麻醉药；用于脊髓麻醉

生化/生理作用

阻断 Ca²⁺ 从肌浆网的电压敏感性释放。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7150 in the slot below. This is an example certificate only and may not be the lot that you receive.

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. T0500000
traceable to USP 1650006

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C

InChI

1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H

InChI key

PPWHTZKZQNXVAE-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

安全信息

象形图

GHS06

警示用语：

Danger

危险声明

H301 - H319 - H336

预防措施声明

P261 - P264 - P270 - P271 - P301 + P310 - P305 + P351 + P338

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 99 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 22 \| 香港与北京 ≥ 32

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