一氯化碘，Iodine monochloride；ACS reagent, 1.10±0.1 I/Cl ratio basis

Iodine monochloride is an interhalogen compound.[1] It forms various complexes with ethyl, isopropyl and t-butylbenzenes. Equilibrium constants for the formation of these complexes have been evaluated.[2] It affords electrically conducting solution on dissolution in polar solvents.[3] Its reaction with thymidine, 3-mono- and 3,3′,5′-trialkylsubstitued thymidine showed that it helps in deglycosylation, anomerization and isomerization of thymidine.[1]

 

Iodine monochloride (ICl) may be employed for the halogenation of methoxy and dimethoxybenzenes.[3] It may be used for the synthesis of flavones.[4]

Iodine monochloride may be used in the synthesis of the following:

• 2-(4-haloisoquinolin-1-yl)ethanol derivatives[5]
• 5-iodosalicylaldehydes[6]
• 5-aryl-6-iodo-8-phenylpyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines[7]
• (±)-1-cyclohexyl-4-iodo-3-methoxybutan-1-ol[8]
• (±)-4-Iodo-3-methoxy-1-phenylbutan-1-ol[8]