γ-环糊精，γ-Cyclodextrin [γ-CD]；produced by Wacker Chemie AG, Burghausen, Germany, ≥90.0% cyclodextrin basis (HPLC)

图片 γ-环糊精，γ-Cyclodextrin [γ-CD]；produced by Wacker Chemie AG, Burghausen, Germany, ≥90.0% cyclodextrin basis (HPLC)
别名：γ-环状糊精，γ环糊精，r环糊精，环八淀粉，环麦芽八糖，沙丁格菌γ-糊精，Cyclomaltooctaose, Cyclooctaamylose, Schardinger γ-Dextrin, gamma-Cyclodextrin

Empirical Formula (Hill Notation): C48H80O40 CAS号: 17465-86-0 分子量: 1297.12 Beilstein: 78740 EC 号: 241-482-4 MDL编号: MFCD00009595 PubChem化学物质编号: 329768038 NACRES: NA.22
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 779431
CAS号: 17465-86-0
MDL号: MFCD00009595
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说明

γ-环糊精（γ-CD）是广泛用于食品和制药工业的环状α-1,4-葡聚糖连接的寡糖。在药物递送中，γ-CD可以用作络合剂，因为它与药物分子形成包合物。环糊精的复合物增加了药物的水溶性和溶解速率，这对于将药物递送至生物系统是有用的。

一般描述

Gamma-cyclodextrin (γ-CD) is a cyclic α-1,4-glucan linked oligosaccharide that is widely used in the food and pharmaceutical industries. In drug delivery, γ-CD can be used as a complexing agent because it forms an inclusion complex with a drug molecule. The complex of cyclodextrin increases the aqueous solubility and dissolution rate of the drug, which is useful for the delivery of the medical agent to a biological system.[1][2]
 

应用

γ-Cyclodextrin can be used as a precursor for the synthesis of:
  • Octakis-(2,3-di-O-methyl-6-O-carboxymethyl)-γ-cyclodextrin sodium salt (ODMCM). ODMCM is used in capillary electrophoresis as a chiral resolving agent.[3]
  • Water-soluble cyclodextrin thioethers derivatives for the transportation of hydrophobic drugs.[4]

法律信息

Cavasol is a registered trademark of Wacker Chemie AG
 
 

属性

等级

produced by Wacker Chemie AG, Burghausen, Germany

质量水平

200

测定

≥90.0% cyclodextrin basis (HPLC)

形式

powder

缺失

≤11.0% loss on drying

SMILES string

[H][C@]1(O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@@H]2[C@@H](COC(C)=O)O[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O

InChI

1S/C48H80O40/c49-1-9-33-17(57)25(65)41(73-9)82-34-10(2-50)75-43(27(67)19(34)59)84-36-12(4-52)77-45(29(69)21(36)61)86-38-14(6-54)79-47(31(71)23(38)63)88-40-16(8-56)80-48(32(72)24(40)64)87-39-15(7-55)78-46(30(70)22(39)62)85-37-13(5-53)76-44(28(68)20(37)60)83-35-11(3-51)74-42(81-33)26(66)18(35)58/h9-72H,1-8H2/t9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m1/s1

InChI key

GDSRMADSINPKSL-HSEONFRVSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

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储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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