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β-烟酰胺腺嘌呤二核苷酸水合物 [氧化型辅酶I],β-Nicotinamide adenine dinucleotide hydrate [β-NAD, β-DPN];Grade I, free acid, 100% (dry weight)

别名:NAD,氧化型辅酶I,辅酶1,辅酶A,二磷酸吡啶核苷酸,β-烟酰胺腺嘌呤二核苷酸水合物,β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, NAD, Nadide

CAS号 53-84-9 经验分子式(希尔表示法) C21H27N7O14P2 · xH2O 分子量 663.43 (anhydrous basis) MDL number MFCD00036253 PubChem Substance ID 329818699
货号(SKU): NAD100-RO
CAS号: 53-84-9
MDL号: MFCD00036253
增值税发票 √ 免费货运 [顺丰 联邦] √
¥1,005.98

产品描述

General description

Nicotinamide adenine dinucleotide (NAD) is a ubiquitously[5] found electron carrier[4] and a cofactor. NAD+ contains an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.[5]

Application

I级NAD(烟酰胺腺嘌呤二核苷酸)用于人类第IV类乙醇脱氢酶的动力学研究。[3]

NAD has been used in in vitro glycogen synthase kinase 3 (GSK3) deacetylation assay.[8] It has also been used as a component in assay mix for the determination of kinetic characteristics using an enzyme-linked kinetic assay.[9]

Biochem/physiol Actions

NAD is also involved in microbial catabolism.[6] β-NAD acts as a substrate for various enzymes in several cellular processes.[7]

The NAD (nicotinamide adenine dinucleotide)/NADH ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo.[1] It works as an electron acceptor.[2]

电子受体

包装

根据固体质量包装。

Quality

纯度:以干重(酶促、CN-配合物和吸光度)计,100% β-NAD;A250nm - A260nm:0.83 ± 0.02,A280nm - A260nm:0.22 ± 0.02
不含污染物:检测不到LDH抑制剂
有机溶剂: =0.05%(GC)

Specifications

吸光系数:在260 nm处为17.6 x 103l x mol-1 x cm-1 ,333 nm处为5.9 x 103l x mol-1 x cm-1(CN-配合物)

Preparation Note

储存条件(工作液):在2至8℃下储存4周后,10 mg/ml的水溶液中至少含有99%的NAD

Other Notes

仅用于生命科学研究。不可用于诊断。

本品是普通型 NAD。

性质

assay100% (dry weight)
formlyophilized
mol wtMr 663.4
packagingpkg of 1 g (10127965001)
pkg of 5 g (10127973001)
mfr. no.Roche
coloroff-white
pH~3.0 (50 mg/mL in water)
λmax260 nm
shipped inwet ice
storage temp.2-8°C
SMILES stringNC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
InChI1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI keyBAWFJGJZGIEFAR-NNYOXOHSSA-N


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 88 | 欧洲Eur. ≥ 126 | 東京Tokyo ≥ 46 | 香港与北京 ≥ 62
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