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乌头碱,Aconitine

别名:(1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-Acetate 14-Benzoate
制造商品牌: 加拿大TRC
货号(SKU): A189875
CAS号: 302-27-2
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¥2,050.00

Product Description

Catalogue NumberA189875
Chemical NameAconitine
Synonyms(1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-Acetate 14-Benzoate;
CAS Number302-27-2
Molecular FormulaC34H47NO11
AppearanceWhite to Off-White Solid
Melting Point>180ºC (dec.)
Molecular Weight645.74
StorageRefrigerator
SolubilityChloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
CategoryStandards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsNeurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In cultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization. Used in producing heart arrhythmia in experimental animals.
 Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesDerbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 55 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 8 | 香港与北京 ≥ 10